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Modular construction of mammalian gene circuits using TALE transcriptional repressors

An important goal of synthetic biology is the rational design and predictable implementation of synthetic gene circuits using standardized and interchangeable parts. However, engineering of complex circuits in mammalian cells is currently limited by the availability of well-characterized and orthogo...

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Sonraí Bibleagrafaíochta
Foilsithe in:Nat Chem Biol
Main Authors: Li, Yinqing, Jiang, Yun, Chen, He, Liao, Weixi, Li, Zhihua, Weiss, Ron, Xie, Zhen
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333066/
https://ncbi.nlm.nih.gov/pubmed/25643171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1736
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