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Rapid, modular and reliable construction of complex mammalian gene circuits

We developed a framework for quick and reliable construction of complex gene circuits for genetically engineering mammalian cells. Our hierarchical framework is based on a novel nucleotide addressing system for defining the position of each part in an overall circuit. With this framework, we demonst...

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Détails bibliographiques
Auteurs principaux: Guye, Patrick, Li, Yinqing, Wroblewska, Liliana, Duportet, Xavier, Weiss, Ron
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763561/
https://ncbi.nlm.nih.gov/pubmed/23847100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt605
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