Systematic Transfer of Prokaryotic Sensors and Circuits to Mammalian Cells

[Image: see text] Prokaryotic regulatory proteins respond to diverse signals and represent a rich resource for building synthetic sensors and circuits. The TetR family contains >10(5) members that use a simple mechanism to respond to stimuli and bind distinct DNA operators. We present a platform...

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Detalhes bibliográficos
Publicado no:ACS Synth Biol
Main Authors: Stanton, Brynne C., Siciliano, Velia, Ghodasara, Amar, Wroblewska, Liliana, Clancy, Kevin, Trefzer, Axel C., Chesnut, Jonathan D., Weiss, Ron, Voigt, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277766/
https://ncbi.nlm.nih.gov/pubmed/25360681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/sb5002856
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