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Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors
Transcription activator-like effectors (TALEs) are modular DNA-binding proteins that can be fused to a variety of effector domains to regulate the epigenome. Nucleotide recognition by TALE monomers follows a simple cipher, making this a powerful and versatile method to activate or repress gene expre...
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| Udgivet i: | Methods Mol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922632/ https://ncbi.nlm.nih.gov/pubmed/26443215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2932-0_7 |
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