Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

Pancreatic ductal adenocarcinoma (PDA) is the most aggressive tumor, showing incidence and mortality values almost identical. Despite remarkable advances in PDA molecular characterization, this disease is still refractory to current treatments. Desmoplastic stroma, a constant hallmark of PDA, has re...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Martínez-Bosch, Neus, Fernández-Barrena, Maite G., Moreno, Mireia, Ortiz-Zapater, Elena, André, Sabine, Gabius, Hans-Joachim, Hwang, Rosa F., Poirier, Françoise, Munné-Collado, Jessica, Iglesias, Mar, Navas, Carolina, Guerra, Carmen, Fernández-Zapico, Martin E., Navarro, Pilar
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332591/
https://ncbi.nlm.nih.gov/pubmed/24812270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3013
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