Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk

Pancreatic ductal adenocarcinoma (PDA) remains one of the most lethal tumor types, with extremely low survival rates due to late diagnosis and resistance to standard therapies. A more comprehensive understanding of the complexity of PDA pathobiology, and especially of the role of the tumor microenvi...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Orozco, Carlos A., Martinez-Bosch, Neus, Guerrero, Pedro E., Vinaixa, Judith, Dalotto-Moreno, Tomás, Iglesias, Mar, Moreno, Mireia, Djurec, Magdolna, Poirier, Françoise, Gabius, Hans-Joachim, Fernandez-Zapico, Martin E., Hwang, Rosa F., Guerra, Carmen, Rabinovich, Gabriel A., Navarro, Pilar
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2018
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PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910865/
https://ncbi.nlm.nih.gov/pubmed/29615514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722434115
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