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Thwarting galectin-induced immunosuppression in breast cancer

Novel therapeutic strategies are needed to counteract breast cancer-associated immunosuppression. Silencing the expression of galectin-1 in a breast carcinoma model inhibited tumor growth and prevented lung metastasis by reducing the frequency and immunosuppressive activity of CD4(+)CD25(+) FOXP3(+)...

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Detalhes bibliográficos
Main Authors: Salatino, Mariana, Dalotto-Moreno, Tomas, Rabinovich, Gabriel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667902/
https://ncbi.nlm.nih.gov/pubmed/23762796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24077
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