Galectin-1 fosters an immunosuppressive microenvironment in colorectal cancer by reprogramming CD8(+) regulatory T cells

Colorectal cancer (CRC) represents the third most common malignancy and the second leading cause of cancer-related deaths worldwide. Although immunotherapy has taken center stage in mainstream oncology, it has shown limited clinical efficacy in CRC, generating an urgent need for discovery of new bio...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Cagnoni, Alejandro J., Giribaldi, María Laura, Blidner, Ada G., Cutine, Anabela M., Gatto, Sabrina G., Morales, Rosa M., Salatino, Mariana, Abba, Martín C., Croci, Diego O., Mariño, Karina V., Rabinovich, Gabriel A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8166155/
https://ncbi.nlm.nih.gov/pubmed/34006646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2102950118
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