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PML degradation fosters an immunosuppressive and pro-metastatic tumor microenvironment

The tumor suppressive functions of promyelocytic leukemia (PML) have been attributed mainly to its inhibition of various malignant properties of tumor cells. Our recent work identifies a PML ubiquitination and degradation pathway, which regulates both cell and non-cell components of the tumor microe...

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Publicat a:Mol Cell Oncol
Autors principals: Wang, Ya-Ting, Chen, Ruey-Hwa
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706947/
https://ncbi.nlm.nih.gov/pubmed/29209651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1364212
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