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Pancreatic cancer-associated stellate cells: A viable target for reducing immunosuppression in the tumor microenvironment
Pancreatic cancer-associated stellate cells secrete soluble factors, such as interleukin-6 (IL-6), that promote the accumulation of myeloid-derived suppressor cells via a signal transducer and activator of transcription 3 (STAT3)-dependent mechanism. Targeting components of the IL-6/JAK/STAT3 signal...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3782129/ https://ncbi.nlm.nih.gov/pubmed/24073373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24891 |
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