Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

Pancreatic ductal adenocarcinoma (PDA) is the most aggressive tumor, showing incidence and mortality values almost identical. Despite remarkable advances in PDA molecular characterization, this disease is still refractory to current treatments. Desmoplastic stroma, a constant hallmark of PDA, has re...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Martínez-Bosch, Neus, Fernández-Barrena, Maite G., Moreno, Mireia, Ortiz-Zapater, Elena, André, Sabine, Gabius, Hans-Joachim, Hwang, Rosa F., Poirier, Françoise, Munné-Collado, Jessica, Iglesias, Mar, Navas, Carolina, Guerra, Carmen, Fernández-Zapico, Martin E., Navarro, Pilar
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332591/
https://ncbi.nlm.nih.gov/pubmed/24812270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3013
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