Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

Pancreatic ductal adenocarcinoma (PDA) is the most aggressive tumor, showing incidence and mortality values almost identical. Despite remarkable advances in PDA molecular characterization, this disease is still refractory to current treatments. Desmoplastic stroma, a constant hallmark of PDA, has re...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Martínez-Bosch, Neus, Fernández-Barrena, Maite G., Moreno, Mireia, Ortiz-Zapater, Elena, André, Sabine, Gabius, Hans-Joachim, Hwang, Rosa F., Poirier, Françoise, Munné-Collado, Jessica, Iglesias, Mar, Navas, Carolina, Guerra, Carmen, Fernández-Zapico, Martin E., Navarro, Pilar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332591/
https://ncbi.nlm.nih.gov/pubmed/24812270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3013
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