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Epigenetic Mechanisms in Hepatic Stellate Cell Activation During Liver Fibrosis and Carcinogenesis

Liver fibrosis is an essential component of chronic liver disease (CLD) and hepatocarcinogenesis. The fibrotic stroma is a consequence of sustained liver damage combined with exacerbated extracellular matrix (ECM) accumulation. In this context, activation of hepatic stellate cells (HSCs) plays a key...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Barcena-Varela, Marina, Colyn, Leticia, Fernandez-Barrena, Maite G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566358/
https://ncbi.nlm.nih.gov/pubmed/31117267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102507
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