Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation

Pancreatic ductal adenocarcinoma (PDA) is the most aggressive tumor, showing incidence and mortality values almost identical. Despite remarkable advances in PDA molecular characterization, this disease is still refractory to current treatments. Desmoplastic stroma, a constant hallmark of PDA, has re...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Martínez-Bosch, Neus, Fernández-Barrena, Maite G., Moreno, Mireia, Ortiz-Zapater, Elena, André, Sabine, Gabius, Hans-Joachim, Hwang, Rosa F., Poirier, Françoise, Munné-Collado, Jessica, Iglesias, Mar, Navas, Carolina, Guerra, Carmen, Fernández-Zapico, Martin E., Navarro, Pilar
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332591/
https://ncbi.nlm.nih.gov/pubmed/24812270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3013
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