Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development

The Rad9 gene is evolutionarily conserved from yeast to human, and plays crucial roles in genomic maintenance, DNA repair and cell cycle checkpoint controls. However, the function of this gene with respect to tumorigenesis is not well understood. A Rad9-null mutation in mice causes embryonic lethali...

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Bibliografiska uppgifter
I publikationen:Cancer Res
Huvudupphovsmän: Hu, Zhishang, Liu, Yuheng, Zhang, Chunbo, Zhao, Yun, He, Wei, Han, Lu, Yang, Leilei, Hopkins, Kevin M., Yang, Xiao, Lieberman, Howard B., Hang, Haiying
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331354/
https://ncbi.nlm.nih.gov/pubmed/18632607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5670
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