Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development

The Rad9 gene is evolutionarily conserved from yeast to human, and plays crucial roles in genomic maintenance, DNA repair and cell cycle checkpoint controls. However, the function of this gene with respect to tumorigenesis is not well understood. A Rad9-null mutation in mice causes embryonic lethali...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Hu, Zhishang, Liu, Yuheng, Zhang, Chunbo, Zhao, Yun, He, Wei, Han, Lu, Yang, Leilei, Hopkins, Kevin M., Yang, Xiao, Lieberman, Howard B., Hang, Haiying
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331354/
https://ncbi.nlm.nih.gov/pubmed/18632607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5670
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