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Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control

Schizosaccharomyces pombe rad9 mutations can render cells sensitive to hydroxyurea (HU), gamma-rays and UV light and eliminate associated checkpoint controls. In vitro mutagenesis was performed on S.pombe rad9 and altered alleles were transplaced into the genome to ascertain the functional significa...

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Hlavní autoři: Hang, Haiying, Rauth, Sarah J., Hopkins, Kevin M., Lieberman, Howard B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC113140/
https://ncbi.nlm.nih.gov/pubmed/11058134
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