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Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control

Schizosaccharomyces pombe rad9 mutations can render cells sensitive to hydroxyurea (HU), gamma-rays and UV light and eliminate associated checkpoint controls. In vitro mutagenesis was performed on S.pombe rad9 and altered alleles were transplaced into the genome to ascertain the functional significa...

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發表在:Nucleic Acids Res
Principais autores: Hang, Haiying, Rauth, Sarah J., Hopkins, Kevin M., Lieberman, Howard B.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2000
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113140/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058134/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.21.4340
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