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Mouse Rad1 deletion enhances susceptibility for skin tumor development
BACKGROUND: Cells are constantly exposed to stresses from cellular metabolites as well as environmental genotoxins. DNA damage caused by these genotoxins can be efficiently fixed by DNA repair in cooperation with cell cycle checkpoints. Unrepaired DNA lesions can lead to cell death, gene mutation an...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2864214/ https://ncbi.nlm.nih.gov/pubmed/20334655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-67 |
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