Antithetical NFATc1–Sox2 and p53–miR200 signaling networks govern pancreatic cancer cell plasticity

In adaptation to oncogenic signals, pancreatic ductal adenocarcinoma (PDAC) cells undergo epithelial–mesenchymal transition (EMT), a process combining tumor cell dedifferentiation with acquisition of stemness features. However, the mechanisms linking oncogene-induced signaling pathways with EMT and...

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Vydáno v:EMBO J
Hlavní autoři: Singh, Shiv K, Chen, Nai-Ming, Hessmann, Elisabeth, Siveke, Jens, Lahmann, Marlen, Singh, Garima, Voelker, Nadine, Vogt, Sophia, Esposito, Irene, Schmidt, Ansgar, Brendel, Cornelia, Stiewe, Thorsten, Gaedcke, Jochen, Mernberger, Marco, Crawford, Howard C, Bamlet, William R, Zhang, Jin-San, Li, Xiao-Kun, Smyrk, Thomas C, Billadeau, Daniel D, Hebrok, Matthias, Neesse, Albrecht, Koenig, Alexander, Ellenrieder, Volker
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4331005/
https://ncbi.nlm.nih.gov/pubmed/25586376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489574
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