Immune-mediated antitumor effect by type 2 diabetes drug, metformin

Metformin, a prescribed drug for type 2 diabetes, has been reported to have anti-cancer effects; however, the underlying mechanism is poorly understood. Here we show that this mechanism may be immune-mediated. Metformin enabled normal but not T-cell–deficient SCID mice to reject solid tumors. In add...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Eikawa, Shingo, Nishida, Mikako, Mizukami, Shusaku, Yamazaki, Chihiro, Nakayama, Eiichi, Udono, Heiichiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4330733/
https://ncbi.nlm.nih.gov/pubmed/25624476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417636112
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller