HSP70 and HSP90 Differentially Regulate Translocation of Extracellular Antigen to the Cytosol for Cross-Presentation

Antigens (Ag) from cancer or virus-infected cells must be internalized by dendritic cells (DCs) to be presented to CD8(+) T cells, which eventually differentiate into Ag-specific cytotoxic T lymphocytes (CTLs) that destroy cancer cells and infected cells. This pathway is termed cross-presentation an...

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Main Authors: Kato, Yu, Kajiwara, Chiaki, Ishige, Ikuo, Mizukami, Shusaku, Yamazaki, Chihiro, Eikawa, Shingo, Kakimi, Kazuhiro, Udono, Heiichiro
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462380/
https://ncbi.nlm.nih.gov/pubmed/23050124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/745962
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