Hsp90-mediated Assembly of the 26 S Proteasome Is Involved in Major Histocompatibility Complex Class I Antigen Processing

Heat shock protein 90 (hsp90) and the proteasome activator PA28 stimulate major histocompatibility complex (MHC) class I antigen processing. It is unknown whether hsp90 influences the proteasome activity to produce T cell epitopes, although association of PA28 with the 20 S proteasome stimulates the...

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Détails bibliographiques
Auteurs principaux: Yamano, Taketoshi, Mizukami, Shusaku, Murata, Shigeo, Chiba, Tomoki, Tanaka, Keiji, Udono, Heiichiro
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Protein Synthesis, Post-Translational Modification, and Degradation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661382/
https://ncbi.nlm.nih.gov/pubmed/18703510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803077200
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