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The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome

Hsp90 has a diverse array of cellular roles including protein folding, stress response and signal transduction. Herein we report a novel function for Hsp90 in the ATP-dependent assembly of the 26S proteasome. Functional loss of Hsp90 using a temperature-sensitive mutant in yeast caused dissociation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Imai, Jun, Maruya, Mikako, Yashiroda, Hideki, Yahara, Ichiro, Tanaka, Keiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC165619/
https://ncbi.nlm.nih.gov/pubmed/12853471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg349
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