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A moonlighting metabolic protein influences repair at DNA double-stranded breaks
Catalytically active proteins with divergent dual functions are often described as ‘moonlighting’. In this work we characterize a new, chromatin-based function of Lys20, a moonlighting protein that is well known for its role in metabolism. Lys20 was initially described as homocitrate synthase (HCS),...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330366/ https://ncbi.nlm.nih.gov/pubmed/25628362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1405 |
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