Loading...

Sequence-specific transcriptional activation is essential for growth suppression by p53.

Although several biochemical features of p53 have been described, their relationship to tumor suppression remains uncertain. We have compared the ability of p53-derived proteins to act as sequence-specific transcriptional (SST) activators with their ability to suppress tumor cell growth, using an im...

Full description

Saved in:
Bibliographic Details
Main Authors: Pietenpol, J A, Tokino, T, Thiagalingam, S, el-Deiry, W S, Kinzler, K W, Vogelstein, B
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC43296/
https://ncbi.nlm.nih.gov/pubmed/8134338
Tags: Add Tag
No Tags, Be the first to tag this record!