Sequence-specific transcriptional activation is essential for growth suppression by p53.

Although several biochemical features of p53 have been described, their relationship to tumor suppression remains uncertain. We have compared the ability of p53-derived proteins to act as sequence-specific transcriptional (SST) activators with their ability to suppress tumor cell growth, using an im...

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Bibliografiske detaljer
Main Authors: Pietenpol, J A, Tokino, T, Thiagalingam, S, el-Deiry, W S, Kinzler, K W, Vogelstein, B
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43296/
https://ncbi.nlm.nih.gov/pubmed/8134338
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