Sequence-specific transcriptional activation is essential for growth suppression by p53.

Although several biochemical features of p53 have been described, their relationship to tumor suppression remains uncertain. We have compared the ability of p53-derived proteins to act as sequence-specific transcriptional (SST) activators with their ability to suppress tumor cell growth, using an im...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pietenpol, J A, Tokino, T, Thiagalingam, S, el-Deiry, W S, Kinzler, K W, Vogelstein, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43296/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8134338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.6.1998
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