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Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes.

The ability of the p53 protein to act as a sequence-specific transcriptional activator suggests that genes induced by p53 may encode critical mediators of p53 tumor suppression. Using a tetracycline-regulated p53 expression system and cDNA library subtraction procedure, we identified several p53-ind...

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Sonraí Bibleagrafaíochta
Main Authors: Buckbinder, L, Talbott, R, Seizinger, B R, Kley, N
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1994
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC45077/
https://ncbi.nlm.nih.gov/pubmed/7938006
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