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Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes.

The ability of the p53 protein to act as a sequence-specific transcriptional activator suggests that genes induced by p53 may encode critical mediators of p53 tumor suppression. Using a tetracycline-regulated p53 expression system and cDNA library subtraction procedure, we identified several p53-ind...

詳細記述

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書誌詳細
主要な著者: Buckbinder, L, Talbott, R, Seizinger, B R, Kley, N
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC45077/
https://ncbi.nlm.nih.gov/pubmed/7938006
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