Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes.
The ability of the p53 protein to act as a sequence-specific transcriptional activator suggests that genes induced by p53 may encode critical mediators of p53 tumor suppression. Using a tetracycline-regulated p53 expression system and cDNA library subtraction procedure, we identified several p53-ind...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7938006/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10640 |
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