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BRCA1 Directs a Selective p53-Dependent Transcriptional Response towards Growth Arrest and DNA Repair Targets

The pathway leading to BRCA1-dependent tumor suppression is not yet clear but appears to involve activities in DNA repair as well as gene transcription. Moreover, it has been shown that BRCA1 can regulate p53-dependent transcription. Because BRCA1 overexpression stabilizes wild-type p53 but does not...

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Sonraí Bibleagrafaíochta
Main Authors: MacLachlan, Timothy K., Takimoto, Rishu, El-Deiry, Wafik S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC133857/
https://ncbi.nlm.nih.gov/pubmed/12024039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4280-4292.2002
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