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PAK1, a gene that can regulate p53 activity in yeast.

The ability of p53 protein to activate transcription is central to its tumor-suppressor function. We describe a genetic selection in Saccharomyces cerevisiae which was used to isolate a mutant strain defective in p53-mediated transcriptional activation. The defect was partially corrected by overexpr...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Thiagalingam, S, Kinzler, K W, Vogelstein, B
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597081/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.6062
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