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PAK1, a gene that can regulate p53 activity in yeast.

The ability of p53 protein to activate transcription is central to its tumor-suppressor function. We describe a genetic selection in Saccharomyces cerevisiae which was used to isolate a mutant strain defective in p53-mediated transcriptional activation. The defect was partially corrected by overexpr...

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Detaylı Bibliyografya
Asıl Yazarlar: Thiagalingam, S, Kinzler, K W, Vogelstein, B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1995
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC41642/
https://ncbi.nlm.nih.gov/pubmed/7597081
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