PAK1, a gene that can regulate p53 activity in yeast.
The ability of p53 protein to activate transcription is central to its tumor-suppressor function. We describe a genetic selection in Saccharomyces cerevisiae which was used to isolate a mutant strain defective in p53-mediated transcriptional activation. The defect was partially corrected by overexpr...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597081/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.6062 |
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