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Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.

Transforming growth factor beta 1 (TGF-beta 1) is a potent growth inhibitor for many cell types, including most epithelial cells. However, the mechanism of growth inhibition is unknown. In skin keratinocytes, TGF-beta 1 has been shown to inhibit growth and to rapidly reduce c-myc expression. It has...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Pietenpol, J A, Holt, J T, Stein, R W, Moses, H L
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1990
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53982/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2187192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3758
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