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Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.

The adenovirus E1A gene product, the simian virus 40 large tumor antigen, and the human papillomavirus E7 protein share a short amino acid sequence that constitutes a domain required for the transforming activity of these proteins. These sequences are also required for these proteins to bind to the...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Chellappan, S, Kraus, V B, Kroger, B, Munger, K, Howley, P M, Phelps, W C, Nevins, J R
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49120/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1316611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.10.4549
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