Restoring redox balance enhances contractility in heart trabeculae from type 2 diabetic rats exposed to high glucose

Hearts from type 2 diabetic (T2DM) subjects are chronically subjected to hyperglycemia and hyperlipidemia, both thought to contribute to oxidizing conditions and contractile dysfunction. How redox alterations and contractility interrelate, ultimately diminishing T2DM heart function, remains poorly u...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Principais autores: Bhatt, Niraj M., Aon, Miguel A., Tocchetti, Carlo G., Shen, Xiaoxu, Dey, Swati, Ramirez-Correa, Genaro, O′Rourke, Brian, Gao, Wei Dong, Cortassa, Sonia
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329481/
https://ncbi.nlm.nih.gov/pubmed/25485897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00378.2014
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