Restoring redox balance enhances contractility in heart trabeculae from type 2 diabetic rats exposed to high glucose

Hearts from type 2 diabetic (T2DM) subjects are chronically subjected to hyperglycemia and hyperlipidemia, both thought to contribute to oxidizing conditions and contractile dysfunction. How redox alterations and contractility interrelate, ultimately diminishing T2DM heart function, remains poorly u...

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發表在:Am J Physiol Heart Circ Physiol
Main Authors: Bhatt, Niraj M., Aon, Miguel A., Tocchetti, Carlo G., Shen, Xiaoxu, Dey, Swati, Ramirez-Correa, Genaro, O′Rourke, Brian, Gao, Wei Dong, Cortassa, Sonia
格式: Artigo
語言:Inglês
出版: American Physiological Society 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329481/
https://ncbi.nlm.nih.gov/pubmed/25485897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00378.2014
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