Restoring redox balance enhances contractility in heart trabeculae from type 2 diabetic rats exposed to high glucose

Hearts from type 2 diabetic (T2DM) subjects are chronically subjected to hyperglycemia and hyperlipidemia, both thought to contribute to oxidizing conditions and contractile dysfunction. How redox alterations and contractility interrelate, ultimately diminishing T2DM heart function, remains poorly u...

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Publicado en:Am J Physiol Heart Circ Physiol
Main Authors: Bhatt, Niraj M., Aon, Miguel A., Tocchetti, Carlo G., Shen, Xiaoxu, Dey, Swati, Ramirez-Correa, Genaro, O′Rourke, Brian, Gao, Wei Dong, Cortassa, Sonia
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Call for Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329481/
https://ncbi.nlm.nih.gov/pubmed/25485897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00378.2014
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