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Quantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes

When selection is strong and mutations are rare, evolution can be thought of as an uphill trajectory in a rugged fitness landscape. In this context the fitness landscape is a directed acyclic graph in which nodes are genotypes and edges lead from lower to higher fitness genotypes that differ by a si...

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Vydáno v:Mol Biosyst
Hlavní autoři: Lobkovsky, Alexander E., Wolf, Yuri I., Koonin, Eugene V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325993/
https://ncbi.nlm.nih.gov/pubmed/23460358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb25553k
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