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Evolution in the weak-mutation limit: Stasis periods punctuated by fast transitions between saddle points on the fitness landscape

A mathematical analysis of the evolution of a large population under the weak-mutation limit shows that such a population would spend most of the time in stasis in the vicinity of saddle points on the fitness landscape. The periods of stasis are punctuated by fast transitions, in lnN(e)/s time (N(e)...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bakhtin, Yuri, Katsnelson, Mikhail I., Wolf, Yuri I., Koonin, Eugene V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848522/
https://ncbi.nlm.nih.gov/pubmed/33472973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2015665118
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