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Evolution of the genetic code: partial optimization of a random code for robustness to translation error in a rugged fitness landscape

BACKGROUND: The standard genetic code table has a distinctly non-random structure, with similar amino acids often encoded by codons series that differ by a single nucleotide substitution, typically, in the third or the first position of the codon. It has been repeatedly argued that this structure of...

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Detalhes bibliográficos
Main Authors: Novozhilov, Artem S, Wolf, Yuri I, Koonin, Eugene V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211284/
https://ncbi.nlm.nih.gov/pubmed/17956616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-2-24
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