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Involvement of Holliday Junction Resolvase in Fluoroquinolone-Mediated Killing of Mycobacterium smegmatis

The absence of the Holliday-junction Ruv resolvase of Mycobacterium smegmatis increased the bacteriostatic and bactericidal activities of the fluoroquinolone moxifloxacin, an important antituberculosis agent. The treatment of ruvAB-deficient cells with thiourea and 2,2′-bipyridyl lowered moxifloxaci...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Long, Quanxin, Du, Qinglin, Fu, Tiwei, Drlica, Karl, Zhao, Xilin, Xie, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325773/
https://ncbi.nlm.nih.gov/pubmed/25534729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04434-14
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