Lethality of Quinolones against Mycobacterium smegmatis in the Presence or Absence of Chloramphenicol

Quinolones were examined for rapid lethal activity against Mycobacterium smegmatis in the presence and absence of chloramphenicol, an inhibitor of protein synthesis. C-8 methoxy, C-6 fluorine, and particular C-7 ring substituents enhanced rapid killing. With the surprising exception of moxifloxacin,...

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Main Authors: Malik, Muhammad, Lu, Tao, Zhao, Xilin, Singh, Anubha, Hattan, Christopher M., Domagala, John, Kerns, Robert, Drlica, Karl
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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Mechanisms of Action: Physiological Effects
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087661/
https://ncbi.nlm.nih.gov/pubmed/15855526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.2008-2014.2005
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