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Role of Cdk1 in the p53-Independent Abrogation of the Postmitotic Checkpoint by Human Papillomavirus E6

Specific types of human papillomavirus (HPV) are strongly associated with the development of cervical carcinoma. The HPV E6 oncoprotein from HPV degrades p53 and abrogates cell cycle checkpoints. Nonetheless, functional p53 has been observed in cervical cancer. We have previously identified a p53-in...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Zhang, Weifang, Liu, Yingwang, Zhao, Ning, Chen, Hanxiang, Qiao, Lijun, Zhao, Weiming, Chen, Jason J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325723/
https://ncbi.nlm.nih.gov/pubmed/25520504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02269-14
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