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The human papillomavirus type 58 E7 oncoprotein modulates cell cycle regulatory proteins and abrogates cell cycle checkpoints

HPV type 58 (HPV-58) is the third most common HPV type in cervical cancer from Eastern Asia, yet little is known about how it promotes carcinogenesis. In this study, we demonstrated that HPV-58 E7 significantly promoted the proliferation and extended the lifespan of primary human keratinocytes (PHKs...

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Detalhes bibliográficos
Main Authors: Zhang, Weifang, Li, Jing, Kanginakudru, Sriramana, Zhao, Weiming, Yu, Xiuping, Chen, Jason J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818596/
https://ncbi.nlm.nih.gov/pubmed/19945133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.10.051
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