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Human Papillomavirus Type 16 E7 oncoprotein engages but does not abrogate the mitotic spindle assembly checkpoint

The mitotic spindle assembly checkpoint (SAC) ensures faithful chromosome segregation during mitosis by censoring kinetochore-microtubule interactions. It is frequently rendered dysfunctional during carcinogenesis causing chromosome missegregation and genomic instability. There are conflicting repor...

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Detalles Bibliográficos
Main Authors: Yu, Yueyang, Munger, Karl
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402702/
https://ncbi.nlm.nih.gov/pubmed/22748180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.06.006
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