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Delocalization of the Microtubule Motor Dynein from Mitotic Spindles by the Human Papillomavirus E7 Oncoprotein is Not Sufficient for Induction of Multipolar Mitoses

Dynein is a minus-end directed microtubule motor that transports numerous cargoes throughout the cell. During mitosis, dynein motor activity is necessary for the positioning of spindle microtubules and has also been implicated in inactivating the spindle assembly checkpoint. Mutations in dynein moto...

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Detalhes bibliográficos
Main Authors: Nguyen, Christine L., McLaughlin-Drubin, Margaret E., Münger, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597155/
https://ncbi.nlm.nih.gov/pubmed/18974113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1303
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