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Regulator of chromatin condensation 1 abrogates the G1 cell cycle checkpoint via Cdk1 in human papillomavirus E7-expressing epithelium and cervical cancer cells

Regulator of chromatin condensation 1 (RCC1) is a major guanine-nucleotide exchange factor for Ran GTPase and plays key roles in nucleo-cytoplasmic transport, mitosis, and nuclear envelope assembly. RCC1 is known to be a critical cell cycle regulator whose loss causes G1 phase arrest, but the molecu...

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Vydáno v:Cell Death Dis
Hlavní autoři: Qiao, Lijun, Zheng, Jingyi, Tian, Yonghao, Zhang, Qishu, Wang, Xiao, Chen, Jason J., Zhang, Weifang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964113/
https://ncbi.nlm.nih.gov/pubmed/29789527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0584-z
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