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Cdc6 contributes to abrogating the G1 checkpoint under hypoxic conditions in HPV E7 expressing cells

The human papillomavirus (HPV) plays a central role in cervical carcinogenesis and its oncogene E7 is essential in this process. We showed here that E7 abrogated the G1 cell cycle checkpoint under hypoxia and analyzed key cell cycle related proteins for their potential role in this process. To furth...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Chen, Hanxiang, Zhang, Qishu, Qiao, Lijun, Fan, Xueli, Zhang, Weifang, Zhao, Weiming, Chen, Jason J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462782/
https://ncbi.nlm.nih.gov/pubmed/28592805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03060-w
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