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Abrogation of the Postmitotic Checkpoint Contributes to Polyploidization in Human Papillomavirus E7-Expressing Cells

High-risk types of human papillomavirus (HPV) are considered the major causative agents of cervical carcinoma. The transforming ability of HPV resides in the E6 and E7 oncogenes, yet the pathway to transformation is not well understood. Cells expressing the oncogene E7 from high-risk HPVs have a hig...

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Detalhes bibliográficos
Main Authors: Heilman, Susan A., Nordberg, Joshua J., Liu, Yingwang, Sluder, Greenfield, Chen, Jason J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648292/
https://ncbi.nlm.nih.gov/pubmed/19129456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02149-08
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