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Abrogation of the Brd4-Positive Transcription Elongation Factor b Complex by Papillomavirus E2 Protein Contributes to Viral Oncogene Repression

The cellular bromodomain protein Brd4 is a major interacting partner of the papillomavirus (PV) E2 protein. Interaction of E2 with Brd4 contributes to viral episome maintenance. The E2-Brd4 interaction also plays an important role in repressing viral oncogene expression from the integrated viral gen...

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Detalhes bibliográficos
Main Authors: Yan, Junpeng, Li, Qing, Lievens, Sam, Tavernier, Jan, You, Jianxin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798453/
https://ncbi.nlm.nih.gov/pubmed/19846528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01647-09
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